SafeMine installs an admin profile that locks Chrome settings. Here’s how to remove it.

  1. Save these steps somewhere safe and close Chrome.
  2. Click the Preferences (System Preferences) icon in your Mac’s menu bar and select Profiles.
  3. Select all AdminPrefs profile(s) and delete them by clicking the minus (−) icon at the bottom.
  4. Once you’ve removed the unwanted “adminprefs” profile(s), open the Terminal app (Go > Utilities > Terminal or press ⌘Space and search Terminal).
  5. Enter the commands below, pressing Enter after each one:
defaults write com.google.Chrome HomepageIsNewTabPage -bool false
defaults write com.google.Chrome NewTabPageLocation -string "https://www.google.com/"
defaults write com.google.Chrome HomepageLocation -string "https://www.google.com/"
defaults delete com.google.Chrome DefaultSearchProviderSearchURL
defaults delete com.google.Chrome DefaultSearchProviderNewTabURL
defaults delete com.google.Chrome DefaultSearchProviderName
  1. Restart Chrome. The issue should be resolved. If not, restart your Mac.

Reference: https://support.google.com/chrome/thread/9350623